Central Centrifugal Cicatricial Alopecia and Fibroproliferative Disorders: Exploring the Association with Uterine Leiomyomas.
Laksha Bala,Aida Kafai Golahmadi,Noha Elshimy
TLDR
The findings from this retrospective cohort study comparing the prevalence of ULs in patients with CCCA to those with lichen planopilaris are supportive of this association and could inform strategies for earlier diagnosis and future therapeutic targets.
摘要
Emerging evidence suggests central centrifugal cicatricial alopecia (CCCA) can be classified as a fibroproliferative disorder, sharing pathophysiological features with conditions such as uterine leiomyomas (ULs) and keloid scarring. Our findings from this retrospective cohort study comparing the prevalence of ULs in patients with CCCA to those with lichen planopilaris are supportive of this association. Further elucidation has the potential to inform strategies for earlier diagnosis and future therapeutic targets.