The L-type amino acid transporter inhibitor, BCH, inhibits myotube BCAA uptake and mitochondrial function without altering myotube insulin sensitivity during insulin resistance in C2C12 myotubes.
The L-type amino acid transporter inhibitor, BCH, inhibits myotube BCAA uptake and mitochondrial function without altering myotube insulin sensitivity during insulin resistance in C2C12 myotubes.
Kipton B. Travis,Kayla J. Ragland,3 作者,Roger A. Vaughan
2025 · DOI: 10.1007/s00592-025-02570-8
Acta Diabetologica · 引用数 0
TLDR
Reduction of BCAA uptake may not improve insulin resistance and may promote mitochondrial dysfunction, demonstrating that reduction of BCAA uptake may not improve insulin resistance and may promote mitochondrial dysfunction.